After instilling an eyedrop, the patient should apply pressure to the lacrimal sac for how long to minimize systemic absorption?

• A. 5 seconds
• B. 15 to 30 seconds
• C. 1 minute
• D. 2 minutes

Answer: (B)

When a drop is placed in the eye, some of the medication can drain through the lacrimal drainage system into the nasal mucosa and enter the bloodstream. Applying gentle pressure to the inner corner of the eye over the lacrimal sac helps block that drainage long enough for more of the drug to stay on the ocular surface and be absorbed where it’s needed, rather than systemically. The recommended duration, 15 to 30 seconds, provides a practical balance: long enough to reduce drainage without causing unnecessary discomfort. Shorter times may not effectively limit drainage, while longer times aren’t typically required for most topical drops and can be awkward for patients.