Opening a new bottle of eyedrops is indicated in which of the following scenarios?

• A. If there is a chance the globe is ruptured or the cornea is cut
• B. If there is an expired date on the bottle
• C. If the bottle is contaminated by touching the eyelids
• D. ALL OF THE ABOVE

Answer: (D)

Opening a fresh bottle of eyedrops is indicated whenever sterility or potency could be compromised. If there is any chance the globe is ruptured or the cornea is cut, starting with a new bottle helps prevent introducing pathogens to a vulnerable eye. An expired bottle may not be sterile or potent, so replacing it with a new bottle ensures the medication remains effective and safe. If the bottle has been contaminated by touching the eyelids, the risk of infection rises, and using a new bottle helps protect the eye. In all of these scenarios, a new, unopened bottle is the safest choice.