Which corneal transplant replaces the entire thickness of the cornea?

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Prepare for the Certified Paraoptometric Assistant (CPOA) Exam. Study with extensive flashcards and multiple choice questions with explanations. Enhance your skills and knowledge to succeed.

Multiple Choice

Which corneal transplant replaces the entire thickness of the cornea?

Explanation:
Full-thickness replacement is achieved with penetrating keratoplasty. This procedure replaces all corneal layers—from the epithelium and Bowman's layer through the stroma to Descemet membrane and endothelium—so the entire thickness of the cornea is replaced. The other options involve partial replacements: lamellar keratoplasty replaces only part of the cornea; deep anterior lamellar keratoplasty (DALK) removes the front layers down to Descemet’s membrane but keeps the patient’s endothelium; Descemet Stripping Endothelial Keratoplasty (DSEK/DSAEK) or Descemet Membrane Endothelial Keratoplasty (DMEK) replace mainly the endothelium (and Descemet’s membrane) with donor tissue, not the full thickness.

Full-thickness replacement is achieved with penetrating keratoplasty. This procedure replaces all corneal layers—from the epithelium and Bowman's layer through the stroma to Descemet membrane and endothelium—so the entire thickness of the cornea is replaced.

The other options involve partial replacements: lamellar keratoplasty replaces only part of the cornea; deep anterior lamellar keratoplasty (DALK) removes the front layers down to Descemet’s membrane but keeps the patient’s endothelium; Descemet Stripping Endothelial Keratoplasty (DSEK/DSAEK) or Descemet Membrane Endothelial Keratoplasty (DMEK) replace mainly the endothelium (and Descemet’s membrane) with donor tissue, not the full thickness.

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