Which glands are located in the eyelid margins and contribute to the lipid layer?

• A. Glands of Krause
• B. Lacrimal gland
• C. Glands of Zeiss
• D. Goblet cells

Answer: (C)

The main idea here is understanding which eyelid glands contribute lipids to the tear film’s outer layer. Glands of Zeiss are sebaceous glands located along the eyelid margin around the eyelashes. Their oily secretions blend with the tear film to form the lipid layer, which helps reduce evaporation and keeps the surface of the eye lubricated.

In contrast, glands of Krause are accessory lacrimal glands that primarily contribute to the aqueous portion of tears; the lacrimal gland itself is the major source of the aqueous layer; and goblet cells in the conjunctiva produce mucin for the innermost, mucus-rich layer that helps with tear film spreading and wetting.